Lake Front Lot With Custom Dock In Place. Dock Has Built In Steps For Easy Swim Access. This Lot Has Long Range Lake Views And Mountain Views. Lake Cherokee is a 300 (+/-) acre private lake at the edge of the Sumter National Forest. It is also referred to as Lake Isaqueena. Of the several private lakes in the Oconee mountain region, Lake Cherokee is the largest . Lake Cherokee is halfway between the Chattooga River and Lake Jocassee. It is convenient to the Tamassee area and the towns of Salem, Walhalla and West Union.